MyBioSource.com's PCDHB12 Antibody (C-term) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunohistochemistry, and Western Blot. The PCDHB12 Antibody (C-term) was generated using PCDHB12 as the antigen and it reacts with Human.
Description
This gene is a member of the protocadherin beta gene
cluster, one of three related gene clusters tandemly linked on
chromosome five. The gene clusters demonstrate an unusual genomic
organization similar to that of B-cell and T-cell receptor gene
clusters. The beta cluster contains 16 genes and 3 pseudogenes,
each encoding 6 extracellular cadherin domains and a cytoplasmic
tail that deviates from others in the cadherin superfamily. The
extracellular domains interact in a homophilic manner to specify
differential cell-cell connections. Unlike the alpha and gamma
clusters, the transcripts from these genes are made up of only one
large exon, not sharing common 3' exons as expected. These neural
cadherin-like cell adhesion proteins are integral plasma membrane
proteins. Their specific functions are unknown but they most likely
play a critical role in the establishment and function of specific
cell-cell neural connections